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Altered heme-mediated modulation of dendritic cell function in sickle cell alloimmunization

Transfusions are the main treatment for patients with sickle cell disease. However, alloimmunization remains a major life-threatening complication for these patients, but the mechanism underlying pathogenesis of alloimmunization is not known. Given the chronic hemolytic state characteristic of sickl...

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Hauptverfasser: Emmanuelle Godefroy, Yunfeng Liu, Patricia Shi, W. Beau Mitchell, Devin Cohen, Stella T. Chou, Deepa Manwani, Karina Yazdanbakhsh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2016-09-01
Schriftenreihe:Haematologica
Online-Zugang:https://haematologica.org/article/view/7815
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