Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) expression in glioblastoma is driven by ETS1- and MYBL2-dependent transcriptional activation

Abstract Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) encodes the 4EBP1 protein, a negative regulator of mRNA translation and a substrate of the mechanistic target of rapamycin (mTOR), whose function and relevance in cancer is still under debate. Here, we analyzed EIF4EBP...

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Autors principals:	Laura Hauffe, Daniel Picard, Julian Musa, Marc Remke, Thomas G. P. Grünewald, Barak Rotblat, Guido Reifenberger, Gabriel Leprivier
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Publishing Group 2022-02-01
Col·lecció:	Cell Death Discovery
Accés en línia:	https://doi.org/10.1038/s41420-022-00883-z
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