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Supersaturated Oxygen Emulsion Mitigates Hypoxia-Driven Corneal Neovascularization after Alkali Burn

Purpose: Alkali burn is a vision-threatening ocular emergency with no targeted acute therapy. We previously identified tissue hypoxia as a key driver and developed a perfluorodecalin-based supersaturated oxygen emulsion (SSOE) that delivers high levels of oxygen topically. In this study, we aim to i...

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Uloženo v:
Hlavní autoři: Asmaa A. Zidan, MD, Elsayed Elbasiony, MD, MSc, Zhirong Lin, PhD, Sheyda Najafi, PhD, Kathryn Pate, PhD, Jia Yin, MD, PhD
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2025-11-01
Edice:Ophthalmology Science
Témata:
Alkali burn
Corneal neovascularization
HIF
Hypoxia-inducible factor
Tissue hypoxia
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2666914525001964
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