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Fundamentals of T Cell Metabolism and Strategies to Enhance Cancer Immunotherapy

Emerging reports show that metabolic pathways can be targeted to enhance T cell-mediated immunity to tumors. Yet, tumors consume key metabolites in the host to survive, thus robbing T cells of these nutrients to function and thrive. T cells are often deprived of basic building blocks for energy in t...

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Detalles Bibliográficos
Principais autores: Guillermo O. Rangel Rivera, Hannah M. Knochelmann, Connor J. Dwyer, Aubrey S. Smith, Megan M. Wyatt, Amalia M. Rivera-Reyes, Jessica E. Thaxton, Chrystal M. Paulos
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fimmu.2021.645242/full
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