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Low GCNT2/I-Branching Glycan Expression Is Associated with Bladder Cancer Aggressiveness

<b>Background/Objectives:</b> Abnormal glycan formation on the cancer cell surface plays a crucial role in regulating tumor functions in bladder cancer. In this study, we investigated the roles of glucosaminyl (<i>N</i>-acetyl) transferase 2 (GCNT2) in bladder cancer progression and immune evasion....

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Autori principali: Yuki Tobisawa, Keita Nakane, Takuya Koie, Tomoki Taniguchi, Masayuki Tomioka, Risa Tomioka-Inagawa, Kota Kawase, Makoto Kawase, Koji Iinuma
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2025-03-01
Serie:Biomedicines
Soggetti:
glycan
GCNT2
I-antigen
bladder cancer
natural killer cell
tumor immunity
Accesso online:https://www.mdpi.com/2227-9059/13/3/682
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