Genetic, Phenotypic, and Clinical Heterogeneity of NPM1-Mutant Acute Myeloid Leukemias

The current classification of acute myeloid leukemia (AML) relies largely on genomic alterations. AML with mutated nucleophosmin 1 (<i>NPM1-mut</i>) is the largest of the genetically defined groups, involving about 30% of adult AMLs and is currently recognized as a distinct entity in the actual AML...

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Detalhes bibliográficos

Principais autores:	Ugo Testa, Elvira Pelosi, Germana Castelli
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-06-01
coleção:	Biomedicines
Assuntos:	acute myeloid leukemia genetic classification mutational profiling transcriptome analysis prognostic stratification clonal evolution
Acesso em linha:	https://www.mdpi.com/2227-9059/11/7/1805
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