Actin and DNA protect histones from degradation by bacterial proteases but inhibit their antimicrobial activity
Histones are small polycationic proteins located in the cell nucleus. Together, DNA and histones are integral constituents of the nucleosomes. Upon apoptosis, necrosis and infection - induced cell death, histones are released from the cell. The extracellular histones have strong antimicrobial activi...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016-08-01
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| coleção: | Frontiers in Microbiology |
| Assuntos: | |
| Acesso em linha: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01248/full |
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