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LINC01088 prevents ferroptosis in glioblastoma by enhancing SLC7A11 via HLTF/USP7 axis

Abstract Background Glioblastoma multiforme (GBM)is a highly aggressive malignancy of the central nervous system characterized by poor survival rates. Ferroptosis, an iron‐dependent cell death pathway, is a promising therapeutic target for GBM. However, current treatments targeting cell death pathwa...

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Principais autores: Yujie Zhou, Zhen Zhao, Cheng Jiang, Chuansheng Nie, Dongdong Xiao, Zhipeng Wu, Hao Yu, Jianglin Zheng, Xuan Wang, Xiaobing Jiang
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2025-03-01
Serier:Clinical and Translational Medicine
Fag:
cystine transporter
ferroptosis
glioblastoma
LncRNA
transcription factor
Online adgang:https://doi.org/10.1002/ctm2.70257
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