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Isolation of Resistomycin from a Terrestrial Actinomycete with TRAIL Resistance-overcoming Activity

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) potently induces apoptosis in most cancer cells, but not in normal cells, and, thus, has attracted intense interest as a promising antitumor agent. Activity-guided fractionation of the culture broth of the actinomycete CKK1172 str...

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Библиографические подробности
Главные авторы: Xuefeidan Liu, Midori A. Arai, Kazufumi Toume and Masami Ishibashi
Формат: Artigo
Язык:Inglês
Опубликовано: SAGE Publishing 2018-01-01
Серии:Natural Product Communications
Online-ссылка:https://doi.org/10.1177/1934578X1801300119
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