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Ultrasensitive Label-Free Detection of Free Thyroxine (T4) in Physiological Ranges Using Aptamer-Functionalized Silicon Nanowire Field Effect Transistors

Thyroxine (T4) is a key hormone regulating metabolic, cardiovascular, and neurodevelopmental processes, yet its clinical quantification still relies on centralized immunoassays that limit rapid or point-of-care monitoring. Here, we present a label-free biosensing platform based on silicon nanowire f...

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Principais autores: Stephanie Klinghammer, Wiana Butko, Alexandra Parichenko, Gylxhane Kastrati, Abdallh Herbawi, Leif Riemenschneider, Gianaurelio Cuniberti
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-05-01
Serier:Biosensors
Fag:
thyroxine
silicon nanowire FET
aptamer biosensor
label-free detection
point-of-care
real-time sensing
Online adgang:https://www.mdpi.com/2079-6374/16/5/274
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