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Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals.

Studies have demonstrated that intensive ART alone is not capable of eradicating HIV-1, as the virus rebounds within a few weeks upon treatment interruption. Viral rebound may be induced from several cellular subsets; however, the majority of proviral DNA has been found in antigen experienced restin...

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書誌詳細
主要な著者: Elizabeth R Wonderlich, Krupa Subramanian, Bryan Cox, Ann Wiegand, Carol Lackman-Smith, Michael J Bale, Mars Stone, Rebecca Hoh, Mary F Kearney, Frank Maldarelli, Steven G Deeks, Michael P Busch, Roger G Ptak, Deanna A Kulpa
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2019-10-01
シリーズ:PLoS Pathogens
オンライン・アクセス:https://doi.org/10.1371/journal.ppat.1008074
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