A primer on tRNAs, tRNA-m1A58 modification, and tRNA derivatives in T-cell activation
Upon antigen recognition, naive CD4+ T cells are activated, exiting quiescence to undergo rapid activation, clonal expansion, and differentiation into effector functions against pathogens. T-cell activation and clonal expansion necessitate the biosynthesis of millions of new protein copies. Recent t...
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2026-01-01
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| Serier: | Frontiers in Cell and Developmental Biology |
| Fag: | |
| Online adgang: | https://www.frontiersin.org/articles/10.3389/fcell.2025.1683213/full |
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