WCK 4873 (INN: Nafithromycin): Structure–activity relationship (SAR) identifying a novel lactone ketolide with activity against Streptococcus pneumoniae (SPN) and Streptococcus pyogenes (SPY)

Ketolides are the fourth generation semisynthetic macrolides derived from erythromycin A, designed to address the limitations of currently available drug treatments including penicillins, macrolides and glycopeptides. Ketolides-the next generation macrolides antibiotics are deliberate to pass the is...

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Detalhes bibliográficos

Principais autores:	Satish Bhavsar, Tadiparthi Ravikumar, Sunil Gupta, Shivaji Pawar, Sanjay Dabhade, Abhijeet K. Kayastha, Prasad Deshpande, Ravindra Yeole, Manohar Nandanwar, Sachin Bhagwat, Mahesh Patel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-01-01
coleção:	Results in Chemistry
Assuntos:	Nafithromycin WCK 4873 Ketolides Streptococcus pneumoniae Amidoxime Ribosomal domain II binding
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211715622004763
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