Kinase–phosphatase balance in exercise adaptation: phosphorylation programs, PTM crosstalk, and actionable gaps

Phosphorylation is set by the opposing activities of kinases and phosphatases and this regulation likely contributes to exercise-induced adaptation. It does so by regulating mitochondrial biogenesis, muscle remodeling, and metabolic flexibility. The process by which exercise activates the AMPK, MAPK...

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Principais autores:	Heming Chen, Zhihui Li, Yanyan Liu, Ying Ji, Junjie Liu, Mi Zheng
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2025-12-01
סדרה:	Frontiers in Sports and Active Living
נושאים:	kinase–phosphatase balance AMPK–Akt–mTOR signaling MAPK phosphatases(MKPs) PHLPP phosphatases phosphoproteomics histidine phosphorylation
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fspor.2025.1743233/full
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