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The molecular mechanisms of mitochondrial dynamics and mitophagy and their complex association with cancer drug resistance

Abstract The development of drug resistance by cancer cells is among the main reasons for cancer treatment failure, greatly limiting the efficacy of chemotherapy, targeted therapy, and immunotherapy. Mitochondria, as the core organelles of cellular energy metabolism, play a key role in the cellular...

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Autori principali: Zhuo Zhao, Yuru Ren, Meijie Yuan, Guobin Liu, Jian Sun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2025-10-01
Serie:Journal of Translational Medicine
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Accesso online:https://doi.org/10.1186/s12967-025-07078-x
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