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Genotype-informed estimation of risk of coronary heart disease based on genome-wide association data linked to the electronic medical record

<p>Abstract</p> <p>Background</p> <p>Susceptibility variants identified by genome-wide association studies (GWAS) have modest effect sizes. Whether such variants provide incremental information in assessing risk for common 'complex' diseases is unclear. We investigated whether measured and imputed g...

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Váldodahkkit: Ding Keyue, Bailey Kent R, Kullo Iftikhar J
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2011-11-01
Ráidu:BMC Cardiovascular Disorders
Liŋkkat:http://www.biomedcentral.com/1471-2261/11/66
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