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Zika virus differentially infects human neural progenitor cells according to their state of differentiation and dysregulates neurogenesis through the Notch pathway

Zika virus (ZIKV) is a mosquito-borne Flavivirus that causes Zika disease with particular neurological complications, including Guillain-Barré Syndrome and congenital microcephaly. Although ZIKV has been shown to directly infect human neural progenitor cells (hNPCs), thereby decreasing their viabil...

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Principais autores: Pauline Ferraris, Marielle Cochet, Rodolphe Hamel, Ivan Gladwyn-Ng, Christian Alfano, Fodé Diop, Déborah Garcia, Loïc Talignani, Claudia N. Montero-Menei, Antoine Nougairède, Hans Yssel, Laurent Nguyen, Muriel Coulpier, Dorothée Missé
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2019-01-01
Serier:Emerging Microbes and Infections
Fag:
Zika
arbovirus
human neural progenitor
Notch
neurogenesis
flavivirus
Online adgang:https://www.tandfonline.com/doi/10.1080/22221751.2019.1637283
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