Combining spatial and single-cell transcriptome data to analyze tertiary lymphoid structures in clear cell renal cell carcinoma reveals prognostic biomarkers

Abstract Background As the predominant and most aggressive subtype of renal cell carcinoma (RCC), clear cell RCC (ccRCC) represents the considerable heterogeneity present across RCC subtypes. Although tertiary lymphoid structures (TLS) are implicated in tumor immunity, their prognostic role and unde...

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主要な著者:	Xuechao Li, Pu Liu, Man Li, Yongzhu Zhou, Tianwei Li, Tao Yang, Jinkai Dong, Chengwei Fu, Yunping Zhu, Lijun Chen, Jie Ma, Wanlin Liu
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2026-01-01
シリーズ:	Journal of Translational Medicine
主題:	Clear cell renal cell carcinoma Prognosis Tertiary lymphoid structures Biomarker Prediction model
オンライン･アクセス:	https://doi.org/10.1186/s12967-026-07713-1
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