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Rational modification of substrate binding site by structure-based engineering of a cellobiose 2-epimerase in Caldicellulosiruptor saccharolyticus

Abstract Background Lactulose, a synthetic disaccharide, has received increasing interest due to its role as a prebiotic, specifically proliferating Bifidobacilli and Lactobacilli and enhancing absorption of calcium and magnesium. The use of cellobiose 2-epimerase (CE) is considered an interesting a...

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主要な著者: Ah-Reum Park, Jin-Sook Kim, Seung-Won Jang, Young-Gyun Park, Bong-Seong Koo, Hyeon-Cheol Lee
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2017-12-01
シリーズ:Microbial Cell Factories
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オンライン・アクセス:http://link.springer.com/article/10.1186/s12934-017-0841-3
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