p85β acts as a transcription cofactor and cooperates with BCLAF1 in the nucleus
Abstract p85β is a regulatory subunit of the phosphoinositide 3-kinase (PI3K). Emerging evidence suggests that p85β goes beyond its role in the PI3K and is functional in the nucleus. In this study, we discover that nuclear p85β is enriched at gene loci and regulates gene transcription and that this...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Portfolio
2025-02-01
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| Edice: | Nature Communications |
| On-line přístup: | https://doi.org/10.1038/s41467-025-56532-3 |
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