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Study on the pharmacokinetics, tissue distribution and excretion of laurolitsine from Litsea glutinosa in Sprague-Dawley rats

Context Laurolitsine is an aporphine alkaloid and exhibits potent antihyperglycemic and antihyperlipidemic effects in ob/ob mice. Objective To investigate the pharmacokinetics, tissue distribution and excretion of laurolitsine. Materials and methods A LC-MS/MS method was established and validated to...

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Principais autores: Yin-Feng Tan, Rui-Qi Wang, Wen-Ting Wang, Ying Wu, Ning Ma, Wei-Ying Lu, Yong Zhang, Xiao-Po Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2021-01-01
coleção:Pharmaceutical Biology
Assuntos:
aporphine alkaloid
lc-ms/ms
Acesso em linha:http://dx.doi.org/10.1080/13880209.2021.1944221
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