Immunomodulatory effects of Eimeria maxima surface antigen (EmSAG) as an IFN-γ inhibitory molecule on peripheral blood mononuclear cells (PBMCs) and T cell subsets in chickens

Abstract Eimeria maxima (E. maxima) infection inhibits the expression of IFN-γ, a cytokine that is essential for the Th1 immune response and plays a key role in combating this parasite. In our preliminary investigations, we identified the E. maxima surface antigen (EmSAG) as an inhibitory molecule o...

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Detalhes bibliográficos

Principais autores:	Xianglin Pu, Yiyuan Zhang, Xinmei Huang, Mingmin Lu, Lixin Xu, Ruofeng Yan, Xiangrui Li, Xiaokai Song
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-05-01
coleção:	Veterinary Research
Assuntos:	IFN-γ inhibitory molecule EmSAG T cell subsets immune evasion immunomodulation
Acesso em linha:	https://doi.org/10.1186/s13567-025-01535-7
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