Mesenchymal stromal cells reduce inflammation and improve lung function in a mouse model of cystic fibrosis lung disease

Abstract Mesenchymal stromal cells (MSCs) are multipotent adult stem cells which possess immunomodulatory and repair capabilities. In this study, we investigated whether MSC therapy could modulate inflammation and lung damage in the lungs of Scnn1b-transgenic mice overexpressing the β-subunit of the...

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Hlavní autoři:	Declan F. Doherty, Lydia E. Roets, Caoifa M. Dougan, Ryan R. Brown, Ian J. Hawthorne, Cecilia O’Kane, Anna D. Krasnodembskaya, Marcus A. Mall, Clifford C. Taggart, Sinéad Weldon
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-12-01
Edice:	Scientific Reports
Témata:	Mesenchymal Stromal Cell Inflammation Emphysema Peroxisome proliferator-activated receptor-γ
On-line přístup:	https://doi.org/10.1038/s41598-024-81276-3
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