Immunization With Skp Delivered on Outer Membrane Vesicles Protects Mice Against Enterotoxigenic Escherichia coli Challenge

Outer membrane vesicles (OMVs) are promising vaccine components because they combine antigen and adjuvant in a single formulation. Detoxified Salmonella enterica strains that express penta-acylated lipid A retain OMV immunogenicity but with reduced reactogenicity. We have previously shown that a rec...

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Bibliographic Details

Main Authors:	Michael P. Hays, Diane Houben, Yang Yang, Joen Luirink, Philip R. Hardwidge
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2018-05-01
Series:	Frontiers in Cellular and Infection Microbiology
Subjects:	enterotoxigenic Escherichia coli vaccines outer membrane vesicles mouse models infection
Online Access:	http://journal.frontiersin.org/article/10.3389/fcimb.2018.00132/full
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