Single-cell RNA and bulk sequencing analysis reveals that formononetin inhibits GTSF1 to exert anti-osteosarcoma effects

As the most common primary malignant bone tumor, osteosarcoma (OS) is characterized by drug resistance and poor prognosis, highlighting the urgent need for promising therapeutic agents. Formononetin (FMN), a natural product derived from Spatholobi Caulis, has been reported to possess anti-tumor prop...

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Autori principali:	Tianyu Xie, Jiming Liang, Chengsen Lin, Wenyu Feng, Mingxiu Yang, Shanhang Li, Liang Xiong, Kai Luo, Feicui Li, Shengping Tang, Shangyu Liu, Qian Huang, Shijie Liao, Jianhong Liu, Yangjie Cai, Fuxing Tang, Haijun Tang, Qingjun Wei, Yunhua Lin, Yun Liu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	AIP Publishing LLC 2025-09-01
Serie:	APL Bioengineering
Accesso online:	http://dx.doi.org/10.1063/5.0266780
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