Aberrant astroglial Kir4.1 activation in the anterior cingulate cortex disrupts neuronal excitability and social behavior

Prenatal herbicide exposure is increasingly linked to neurodevelopmental disorders, yet effective pharmacological interventions remain lacking due to unclear pathogenic mechanisms. Here, we demonstrate that prenatal exposure to glufosinate ammonium (GLA), a widely used herbicide, triggers autism-lik...

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Detalhes bibliográficos

Principais autores:	Zhengmao Li, Yixuan Zhang, Yan Chen, Ying Zhang, Yunlong Pan, Kerui Wang, Chen Li, Xiangyu Zhao, Weikang Hu, Yifan Luo, Jiawen Cheng, Hongzhen Zhang, Kohji Fukunaga, Yankai Xia, Jiandong Jiang, Xiuxiu Liu, Feng Han, Yingmei Lu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-04-01
coleção:	Acta Pharmaceutica Sinica B
Assuntos:	Autism spectrum disorder Glufosiante ammonium Offspring Anterior cingulate cortex Astrocyte Pyramidal neurons
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211383526000584
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