Kinetic Analysis Misinterpretations Due to the Occurrence of Enzyme Inhibition by Reaction Product: Comparison between Initial Velocities and Reaction Time Course Methodologies

The Michaelis–Menten equation (MME) has been extensively used in biochemical reactions, but it is not appropriate when the reaction product inhibits the enzyme. Under these circumstances, each determined initial velocity, v₀, is one experimental point that actually belongs to a different...

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Päätekijät:	Joana M. C. Fernandes, Albino A. Dias, Rui M. F. Bezerra
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2021-12-01
Sarja:	Applied Sciences
Aiheet:	enzyme inhibition integrated Michaelis–Menten equations reaction product inhibition two mutually exclusive inhibitors
Linkit:	https://www.mdpi.com/2076-3417/12/1/102
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