Detection of EGFR Activating and Resistance Mutations by Droplet Digital PCR in Sputum of EGFR-Mutated NSCLC Patients

Background: Proof of the T790M resistance mutation is mandatory if patients with EGFR -mutated non-small cell lung cancer (NSCLC) progress under first- or second-generation tyrosine kinase inhibitor therapy. In addition to rebiopsy, analysis of plasma circulating tumor DNA is used to detect T790M re...

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Detalhes bibliográficos

Principais autores:	Klaus Hackner, Anna Buder, Maximilian J Hochmair, Matthaeus Strieder, Christina Grech, Hannah Fabikan, Otto C. Burghuber, Peter Errhalt, Martin Filipits
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SAGE Publishing 2021-02-01
coleção:	Clinical Medicine Insights: Oncology
Acesso em linha:	https://doi.org/10.1177/1179554921993072
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