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[177Lu]Lu-DOTA-TATE tumour and organ time-activity curves: prediction from a single-time-point [68Ga]Ga-DOTA-TATE PET/CT measurement

Abstract Aim Predicting the time-activity curve (TAC) of [177Lu]Lu-DOTA-TATE for organs at risk and neuroendocrine tumours (NETs) is an essential element in the calculation of the absorbed dose (AD) and a critical step for individualising peptide receptor radionuclide therapy (PRRT) treatment planni...

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Auteurs principaux: Valentina Vasić, Johan Gustafsson, Elham Yousefzadeh-Nowshahr, Ambros J. Beer, Katarina Sjögreen Gleisner, Gerhard Glatting
Format: Artigo
Langue:Inglês
Publié: SpringerOpen 2026-01-01
Collection:EJNMMI Physics
Sujets:
PRRT
PBPK model
Single-Time-Point [68Ga]Ga-DOTA-TATE
Error model analysis
TAC prediction
Accès en ligne:https://doi.org/10.1186/s40658-025-00826-4
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