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Paternal sepsis induces alterations of the sperm methylome and dampens offspring immune responses—an animal study

Abstract Background Sepsis represents the utmost severe consequence of infection, involving a dysregulated and self-damaging immune response of the host. While different environmental exposures like chronic stress or malnutrition have been well described to reprogram the germline and subsequently of...

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Detalhes bibliográficos
Principais autores: Katharina Bomans, Judith Schenz, Sandra Tamulyte, Dominik Schaack, Markus Alexander Weigand, Florian Uhle
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-06-01
coleção:Clinical Epigenetics
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Acesso em linha:http://link.springer.com/article/10.1186/s13148-018-0522-z
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