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Aspirin Recapitulates Features of Caloric Restriction

Summary: The age-associated deterioration in cellular and organismal functions associates with dysregulation of nutrient-sensing pathways and disabled autophagy. The reactivation of autophagic flux may prevent or ameliorate age-related metabolic dysfunctions. Non-toxic compounds endowed with the cap...

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Principais autores: Federico Pietrocola, Francesca Castoldi, Maria Markaki, Sylvie Lachkar, Guo Chen, David P. Enot, Sylvere Durand, Noelie Bossut, Mingming Tong, Shoaib A. Malik, Friedemann Loos, Nicolas Dupont, Guillermo Mariño, Nejma Abdelkader, Frank Madeo, Maria Chiara Maiuri, Romano Kroemer, Patrice Codogno, Junichi Sadoshima, Nektarios Tavernarakis, Guido Kroemer
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018-02-01
Serier:Cell Reports
Online adgang:http://www.sciencedirect.com/science/article/pii/S221112471830192X
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