Phytosphingosine Alleviates Cigarette Smoke‐Induced Bronchial Epithelial Cell Senescence in Chronic Obstructive Pulmonary Disease by Targeting the Free Fatty Acid Receptor 4

ABSTRACT Chronic obstructive pulmonary disease (COPD) is a complex and irreversible respiratory disorder with a poor prognosis and a lack of effective pharmaceutical treatment. Our previous metabolomics study identified phytosphingosine (PHS) as a key differential metabolite in COPD that is positive...

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Autori principali:	Yuan Zhan, Zhesong Deng, Ruonan Yang, Shanshan Chen, Jiaheng Zhang, Yating Zhang, Hao Fu, Qian Huang, Yiya Gu, Zhilin Zeng, Jinkun Chen, Jixian Zhang, Jixing Wu, Jungang Xie
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2025-09-01
Serie:	MedComm
Soggetti:	cellular senescence chronic obstructive pulmonary disease cigarette smoke free fatty acid receptor 4 phytosphingosine
Accesso online:	https://doi.org/10.1002/mco2.70345
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