Improving In Vitro–In Vivo Correlation (IVIVC) for Lipid-Based Formulations: Overcoming Challenges and Exploring Opportunities

Lipid-based formulations (LBFs) play a crucial role in enhancing the oral bioavailability of poorly water-soluble drugs by leveraging lipid digestion and solubilization processes. However, developing robust in vitro–in vivo correlations (IVIVCs) for LBFs presents unique challenges due to the complex...

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Auteurs principaux:	Arnaud Bourderi-Cambon, Khaled Fadhlaoui, Ghislain Garrait, Emmanuelle Lainé, Imen Dhifallah, Manon Rossano, Philippe Caisse, Eric Beyssac
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2025-10-01
Collection:	Pharmaceutics
Sujets:	lipid-based formulations in vitro–in vivo correlation in vitro dissolution in vitro digestion in silico prediction tools
Accès en ligne:	https://www.mdpi.com/1999-4923/17/10/1310
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