Herpes simplex virus infection induces necroptosis of neurons and astrocytes in human fetal organotypic brain slice cultures

Abstract Background Herpes simplex virus (HSV) encephalitis (HSE) is a serious and potentially life-threatening disease, affecting both adults and newborns. Progress in understanding the virus and host factors involved in neonatal HSE has been hampered by the limitations of current brain models that...

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Autors principals:	Ahmad S. Rashidi, Diana N. Tran, Caithlin R. Peelen, Michiel van Gent, Werner J. D. Ouwendijk, Georges M. G. M. Verjans
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2024-02-01
Col·lecció:	Journal of Neuroinflammation
Matèries:	Herpes simplex virus Encephalitis Human brain Organotypic cultures Neurotropism Neurovirulence
Accés en línia:	https://doi.org/10.1186/s12974-024-03027-5
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