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Inhibition of lysosomal phospholipase A2 predicts drug-induced phospholipidosis

Phospholipidosis, the excessive accumulation of phospholipids within lysosomes, is a pathological response observed following exposure to many drugs across multiple therapeutic groups. A clear mechanistic understanding of the causes and implications of this form of drug toxicity has remained elusive...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vania Hinkovska-Galcheva, Taylour Treadwell, Jonathan M. Shillingford, Angela Lee, Akira Abe, John J.G. Tesmer, James A. Shayman
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2021-01-01
Saila:Journal of Lipid Research
Gaiak:
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S0022227521000717
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