Unravelling bisphenol A pharmacokinetics using physiologically based pharmacokinetic modeling

Physiologically based pharmacokinetic (PBPK) models integrate both chemical- and system-specific information into a mathematical framework, offering a mechanistic approach to predict the internal dose metrics of a chemical and an ability to perform species and dose extrapolations. Bisphenol A (BPA),...

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Hlavní autoři:	Xiaoxia eYang, Jeffrey W Fisher
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2015-01-01
Edice:	Frontiers in Pharmacology
Témata:	bisphenol A pharmacokinetics PBPK Species extrapolation age-dependent pharmacokinetics dosimetry.
On-line přístup:	http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00292/full
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