The establishment of an expected concentration reference range for eltrombopag in the individualized treatment of pediatric immune thrombocytopenia

BackgroundDifferences in the clinical efficacy and adverse drug reactions (ADRs) of eltrombopag (ELT) in children with immune thrombocytopenia (ITP) may be positively correlated with the serum trough concentration of ELT. Individual pharmacokinetic variations primarily contribute to differences in E...

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Principais autores:	Nan Wang, Shuyue Dong, Yixin Sun, Jingjing Liu, Zhifa Wang, Jingyao Ma, Xiaoling Wang, Runhui Wu, Xiaoling Cheng
格式:	Artigo
語言:	Inglês
出版:	Frontiers Media S.A. 2025-08-01
叢編:	Frontiers in Pharmacology
主題:	eltrombopag immune thrombocytopenia children individualized treatment therapeutic drug monitoring
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1597641/full
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