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Peri‐arterial pathways for clearance of α‐Synuclein and tau from the brain: Implications for the pathogenesis of dementias and for immunotherapy

Abstract Introduction Accumulation of amyloid beta (Aβ), α‐synuclein (αSyn), and tau in dementias indicates their age‐related failure of elimination from the brain. Aβ is eliminated along basement membranes in walls of cerebral arterioles and leptomeningeal arteries (intramural peri‐arterial drainag...

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Bibliografski detalji
Glavni autori: Jacqui Nimmo, David A. Johnston, J. C. Dodart, Matthew T. MacGregor‐Sharp, Roy O. Weller, James A. R. Nicoll, Ajay Verma, Roxana O. Carare
Format: Artigo
Jezik:Inglês
Izdano: Wiley 2020-01-01
Serija:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Teme:
Online pristup:https://doi.org/10.1002/dad2.12070
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