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RNA G‐Quadruplex RIBOTAC‐Mediated Targeted Degradation of lncRNA TERRA

Abstract Long noncoding RNAs (lncRNAs) regulate gene expression and play crucial roles in development and disease, including cancer. One important but still poorly understood lncRNA is TERRA (telomeric repeat‐containing RNA), transcribed from telomeres and essential for telomere maintenance, genome...

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Principais autores: Elias Khaskia, Dipak Dahatonde, Raphael I. Benhamou
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2025-12-01
Serier:Advanced Science
Fag:
alternative lengthening of telomeres
G‐quadruplex
lncRNA
RIBOTAC
small molecules
targeted degradation
Online adgang:https://doi.org/10.1002/advs.202512715
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