Endogenous Sox8 is a critical factor for timely remyelination and oligodendroglial cell repletion in the cuprizone model

Abstract Genome-wide association studies identified a single nucleotide polymorphism (SNP) downstream of the transcription factor Sox8, associated with an increased risk of multiple sclerosis (MS). Sox8 is known to influence oligodendrocyte terminal differentiation and is involved in myelin maintena...

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Autors principals:	David Freudenstein, Magdalena Lippert, Janina Sophie Popp, Jessica Aprato, Michael Wegner, Elisabeth Sock, Stefanie Haase, Ralf A. Linker, María Nazareth González Alvarado
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2023-12-01
Col·lecció:	Scientific Reports
Accés en línia:	https://doi.org/10.1038/s41598-023-49476-5
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