Transient Lipid-Protein Structures and Selective Ganglioside Uptake During α-Synuclein-Lipid Co-aggregation

α-Synuclein is a membrane-interacting protein involved in Parkinson’s disease. Here we have investigated the co-association of α-synuclein and lipids from ganglioside-containing model membranes. Our study relies on the reported importance of ganglioside lipids, which are found in high amounts in neu...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Ricardo Gaspar, Ilaria Idini, Göran Carlström, Sara Linse, Emma Sparr
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2021-02-01
Цуврал:	Frontiers in Cell and Developmental Biology
Нөхцлүүд:	amyloid formation lipid-protein co-assembly lipid selectivity cryo-EM NMR
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fcell.2021.622764/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!