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Oral administration of lysozyme protects against injury of ileum via modulating gut microbiota dysbiosis after severe traumatic brain injury

ObjectiveThe current study sought to clarify the role of lysozyme-regulated gut microbiota and explored the potential therapeutic effects of lysozyme on ileum injury induced by severe traumatic brain injury (sTBI) and bacterial pneumonia in vivo and in vitro experiments.MethodsMale 6–8-week-old spec...

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Principais autores: Weijian Yang, Caihua Xi, Haijun Yao, Qiang Yuan, Jun Zhang, Qifang Chen, Gang Wu, Jin Hu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-01-01
coleção:Frontiers in Cellular and Infection Microbiology
Assuntos:
traumatic brain injury
gut microbiota
Paneth cell
lysozyme
bacterial translocation
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1304218/full
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