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Fedratinib in 2025 and beyond: indications and future applications

Abstract: Dysregulated JAK/STAT signaling underlies the pathogenesis of myelofibrosis, a myeloproliferative neoplasm characterized by cytopenias, splenomegaly, and constitutional symptoms. JAK inhibitors, such as fedratinib, are the primary therapeutic option for patients with high-risk or symptomat...

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Principais autores: Alexander Coltoff, John Mascarenhas
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2025-04-01
Series:Blood Advances
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2473952925001041
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