Critical redundant functions of the adapters Grb2 and Gads in platelet (hem)ITAM signaling in mice

Platelets are essential for normal hemostasis; however, pathological conditions can also trigger unwanted platelet activation precipitating thrombosis and ischemic damage of vital organs such as the heart or brain. Glycoprotein (GP)VI- and C-type lectin-like receptor 2 (CLEC-2)-mediated (hem)immunor...

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Autori principali:	Timo Vögtle, Ayesha A. Baig, Julia Volz, Timothy B. Duchow, Irina Pleines, Sebastian Dütting, Lars Nitschke, Stephen P. Watson, Bernhard Nieswandt
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis Group 2020-08-01
Serie:	Platelets
Soggetti:	adapter proteins hemostasis itam mice signaling
Accesso online:	http://dx.doi.org/10.1080/09537104.2019.1709633
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