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Effect of CRISPR Knockout of AXIN1 or ARID1A on Proliferation and Migration of Porcine Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is an aggressive disease lacking effective treatment. Animal models of HCC are necessary for preclinical evaluation of the safety and efficacy of novel therapeutics. Large animal models of HCC allow testing image-guided locoregional therapies, which are widely used in...

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Furkejuvvon:
Váldodahkkit: Lobna Elkhadragy, Kimia Dasteh Goli, William M. Totura, Maximillian J. Carlino, Maureen R. Regan, Grace Guzman, Lawrence B. Schook, Ron C. Gaba, Kyle M. Schachtschneider
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2022-05-01
Ráidu:Frontiers in Oncology
Fáttát:
liver cancer
hepatocellular carcinoma
porcine models
ARID1A
AXIN1
CRISPR
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fonc.2022.904031/full
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