Optimized Bioconversion of Naringenin to Hesperetin in Escherichia coli With Halide Methyltransferase‐Mediated S‐Adenosylmethionine Regeneration

ABSTRACT Hesperetin is a bioactive flavonoid with potential applications in pharmaceuticals and nutraceuticals, yet its low natural abundance limits commercial use. In this study, a two‐step whole‐cell bioconversion process was developed for the microbial production of hesperetin from naringenin in...

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Hlavní autoři:	Maik Wildhagen, Nina Malke, Qimin Wang, Xiaoying Zhuang, Sascha Beutel
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Maximum Academic Press 2026-02-01
Edice:	Engineering in Life Sciences
Témata:	halide methyltransferase hesperetin HpaBC O‐methyltransferase whole‐cell biocatalysis
On-line přístup:	https://doi.org/10.1002/elsc.70069
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