Testis-specific knockout of Elovl4 reduces sperm motility and fertility in male mice

Abstract Fatty acid elongase 4 (Elovl4) is a crucial enzyme in mammals for synthesizing very long-chain fatty acids (VLC-FAs) with more than 26 carbons in a few specific tissues. In the testis and the sperm produced therefrom, the primary elongation products of Elovl4 are very long-chain polyunsatur...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Shuangli Wen, Yuhong Wang, Shisai Yang, Xuan Zhao, Jiaxi Ju, Hongjin Yang, Guiming Zhu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-01-01
coleção:	Scientific Reports
Assuntos:	Elovl4 VLC-PUFAs Testis Male fertility β-defensins
Acesso em linha:	https://doi.org/10.1038/s41598-025-33558-7
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!