BMP2 gene transfer induces pericardial effusion and inflammatory response in the ischemic porcine myocardium

Pro-angiogenic gene therapy is being developed to treat coronary artery disease (CAD). We recently showed that bone morphogenetic protein 2 (BMP2) and vascular endothelial growth factor-A synergistically regulate endothelial cell sprouting in vitro. BMP2 was also shown to induce endocardial angiogen...

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Главные авторы:	H. H. Pulkkinen, A. Kivistö-Rahnasto, H. Korpela, M. Heikkilä, N. Järveläinen, S. Siimes, L. Kilpeläinen, N. Laham-Karam, S. Ylä-Herttuala, J. P. Laakkonen
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2023-11-01
Серии:	Frontiers in Cardiovascular Medicine
Предметы:	bone morphogenetic protein 2 BMP2 myocardial ischemia ischemic heart disease gene therapy inflammation
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fcvm.2023.1279613/full
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