HIV proviral genetic diversity, compartmentalization and inferred dynamics in lung and blood during long-term suppressive antiretroviral therapy.

The lung is an understudied site of HIV persistence. We isolated 898 subgenomic proviral sequences (nef) by single-genome approaches from blood and lung from nine individuals on long-term suppressive antiretroviral therapy (ART), and characterized genetic diversity and compartmentalization using for...

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Autori principali:	Aniqa Shahid, Bradley R Jones, Julia S W Yang, Winnie Dong, Tawimas Shaipanich, Kathryn Donohoe, Chanson J Brumme, Jeffrey B Joy, Janice M Leung, Zabrina L Brumme
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Public Library of Science (PLoS) 2022-11-01
Serie:	PLoS Pathogens
Accesso online:	https://doi.org/10.1371/journal.ppat.1010613
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