Relevance of porcine intestinal organoids as a surrogate for animal experimentation: application to the investigation of host–virus interactions during porcine coronavirus infection

Abstract The small intestine, a part of the digestive system, absorbs nutrients and plays a role in immune protection against viruses that can disrupt its activity. Currently, to analyse these functions, studies rely on in vivo (animals) or in vitro (most often immortalized cell lines) experiments....

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Opis bibliograficzny

Główni autorzy:	Ludivine Percevault, Léon-Charles Tranchevent, Lionel Bigault, Maxime Berthaud, Damien Le Gloahec, Pierrick Lucas, Flora Carnet, Aurélie Le Roux, Gérald Le Diguerher, Frédéric Paboeuf, Daniel Dory, Yannick Blanchard, Béatrice Grasland, Maud Contrant
Format:	Artigo
Język:	Inglês
Wydane:	BMC 2025-11-01
Seria:	Veterinary Research
Hasła przedmiotowe:	Intestinal organoids piglet jejunum transmissible gastroenteritis virus host–virus interactions coronavirus swine
Dostęp online:	https://doi.org/10.1186/s13567-025-01657-y
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